
Thermo Fisher Scientific Phospho-SQSTM1 (Ser349) Polyclonal Antibody
Phospho-SQSTM1 (Ser349) 항체로 인간, 마우스, 랫트 시료에서 사용 가능. Western blot 및 ELISA에 적합하며, 높은 특이성과 재현성을 제공. 액상 형태로 -20°C에서 보관. 연구용으로 NF-κB 신호전달 관련 단백질 분석에 활용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S349 of human SQSTM1/p62 (NP_003891.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914352 |
Product Specific Information
Positive test controls include: HeLa, C6, NIH/3T3.
The target is usually found in the following locations: Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome.
Immunogen sequence: DPSTG
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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