Thermo Fisher Scientific CRYAB Recombinant Rabbit Monoclonal Antibody (ARC1672)
CRYAB 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF, ELISA 등에 사용 가능. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형식. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CRYAB Recombinant Rabbit Monoclonal Antibody (ARC1672)
Thermo Fisher Scientific CRYAB Recombinant Rabbit Monoclonal Antibody (ARC1672)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1672 |
| Immunogen | Synthetic peptide corresponding to amino acids 76–175 of human CRYAB (P02511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849724 |
Product Specific Information
Immunogen sequence:
SVNLDVKHFS PEELKVKVLG DVIEVHGKHE ERQDEHGFIS REFHRKYRIP ADVDPLTITS SLSSDGVLTV NGPRKQVSGP ERTIPITREE KPAVTAAPKK
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index of the lens.
The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest and composed of two primary gene products—alpha-A and alpha-B.
Alpha-Crystallin comprises approximately 40% of total lens protein composition. In addition to maintaining proper refractive index, it functions in a chaperone-like manner by preventing the formation of aggregates that may lead to cataract formation.
Phosphorylated states of alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance. Alpha-B crystallin has been linked to Alexander's disease, where it accumulates in brain cells of affected individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 관련 이미지가 있을 경우 이 섹션에 배치)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.