Thermo Fisher Scientific PPM1B Monoclonal Antibody (OTI3F2), TrueMAB
PPM1B 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포 분석에 적합합니다. HEK293T 세포에서 생산된 전장 인간 재조합 단백질을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F2 |
| Immunogen | Full length human recombinant protein of human PPM1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by this gene belongs to the PP2C family of Ser/Thr protein phosphatases, which are negative regulators of cell stress response pathways.
PPM1B dephosphorylates cyclin-dependent kinases (CDKs), potentially regulating cell cycle control.
Overexpression of this phosphatase may lead to cell growth arrest or cell death.
Alternative splicing results in multiple transcript variants encoding different isoforms.
Additional variants have been described but may not represent full-length sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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