Thermo Fisher Scientific eIF4G3 Polyclonal Antibody
Human eIF4G3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 사용 가능. 정제된 액상 형태로 제공되며, PBS와 글리세롤 버퍼에 보존. 단백질 번역 조절 연구 및 암 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1000–1200 of human EIF4G3 (NP_003751.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805857 |
Product Specific Information
Immunogen sequence:
HKEAKIEEQE EQRKVQQLMT KEKRRPGVQR VDEGGWNTVQ GAKNSRVLDP SKFLKITKPT IDEKIQLVPK AQLGSWGKGS SGGAKASETD ALRSSASSLN RFSALQPPAP SGSTPSTPVE FDSRRTLTSR GSMGREKNDK PLPSATARPN TFMRGGSSKD LLDNQSQEEQ RREMLETVKQ LTGGVDVERN STEAERNKTR E
Positive Samples: LO2, HeLa
Target Information
The protein encoded by the EIF4G3 gene is part of the eIF4F protein complex, which plays a critical role in mRNA cap recognition and transport of mRNAs to the ribosome. A microRNA (miR-520c-3p) negatively regulates synthesis of this protein, resulting in decreased protein translation and cell proliferation. Thus, EIF4G3 is a key component in the anti-tumor activity of miR-520c-3p.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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