Thermo Fisher Scientific LRFN2/SALM1 Polyclonal Antibody
LRFN2/SALM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 제품입니다. 인간, 마우스, 랫트 반응성이 있으며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LRFN2/SALM1, amino acids 401–500 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LRFN2 is one of a family of five transmembrane glycoproteins highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR), immunoglobulin-like (Ig), and fibronectin type III (Fn) transmembrane domain structures with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family.
Expression of LRFN1, -3, and -4 mRNA is detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression is primarily restricted to more mature cells. LRFN1, -2, and -4 bind to PDZ domains of postsynaptic PSD95, redistributing PSD95 to the cell periphery. These proteins may play roles in the developing and/or mature vertebrate nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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