Thermo Fisher Scientific PYCARD Polyclonal Antibody
Thermo Fisher Scientific의 PYCARD 폴리클로날 항체는 인간, 마우스, 랫트에서 반응하며 아폽토시스 및 염증 연구에 적합합니다. Western blot, IHC, ICC/IF에 사용 가능하며 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PYCARD Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PYCARD (Accession Q9ULZ3), corresponding to amino acid residues M1–L32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903368 |
Product Specific Information
Antibody detects endogenous levels of total TMS1/ASC.
Target Information
PYCARD functions as a key mediator in apoptosis and inflammation. It promotes caspase-mediated apoptosis involving caspase-8 and -9, activates the mitochondrial apoptotic pathway, and mediates BAX-dependent apoptosis. It is involved in macrophage pyroptosis and acts as an adapter in inflammasome assembly, activating caspase-1 and promoting cytokine processing. PYCARD interacts with pattern recognition receptors such as NLRP2, NLRP3, AIM2, and IFI16, and may regulate NF-κB signaling. Isoforms exhibit regulatory roles in inflammasome activation and cytokine maturation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.