Thermo Fisher Scientific Phospho-MKK7 (Ser271, Thr275) Polyclonal Antibody
인산화된 MKK7(Ser271, Thr275)을 특이적으로 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, Flow, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, 안정적 액상 형태로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human MKK7 around the phosphorylation site of Ser271/Thr275 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is itself phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK.
This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants exist, but only one has been well defined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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