Thermo Fisher Scientific PHF6 Polyclonal Antibody
PHF6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, IP 등 다양한 응용에 적합. Human에 반응하며 Bovine 및 Orangutan에서도 예측 반응. 항원 친화 크로마토그래피로 정제, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 and 175 of human PHD finger protein 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
Target Information
This gene belongs to the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein containing two PHD-type zinc finger domains, suggesting a role in transcriptional regulation and localization to the nucleolus.
Mutations in this gene are associated with Borjeson-Forssman-Lehmann syndrome (BFLS), characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, facial edema, narrow palpebral fissures, and large ears.
Alternate transcriptional splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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