Thermo Fisher Scientific DCP1A Polyclonal Antibody
Thermo Fisher Scientific의 DCP1A Polyclonal Antibody는 인간 DCP1A 단백질(225-275 aa)에 특이적인 토끼 다클론 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of human DCP1 Decapping Enzyme Homolog A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. Smads relay signals from the cell membrane to the nucleus and influence specific gene transcription. Smad4 is essential for TGF-beta-induced transcriptional activation, forming complexes with phosphorylated receptor-associated Smads.
SMIF (Smad4-interacting protein) and Smad4 form a complex with TGF-beta and BMP4, facilitating nuclear translocation. The Smad4-interacting domain within the N-terminal 100 amino acids of SMIF is critical for this process. The human SMIF gene is ubiquitously expressed and encodes a protein with an approximate molecular mass of 70 kDa.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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