Thermo Fisher Scientific ZNF174 Polyclonal Antibody
Human ZNF174 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ZNF174 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZNF174. Recombinant protein control fragment (Product #RP-102392) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789545 |
Product Specific Information
Immunogen sequence:
VSGPQEALSQ LRQLCRQWLQ PELHTKEQIL ELLVMEQFLT ILPPEIQARV RHRCPMSSKE IVTLVEDFHR ASKKPKQWVA VCMQGQKVLL EKTGSQLGEQ ELPDFQPQTP RRDLRESSPA EPSQAGAYDR LSPHHWEKSP LLQ
Target Information
ZNF174 (also known as ZSCAN8 or AW-1) is a transcriptional repressor belonging to the Krueppel C2H2-type zinc-finger protein family. It is expressed in various tissues including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney, and thymus, with predominant expression in adult ovary and testis.
ZNF174 represses promoter activities of PDGF-B and TGF beta1, localizes to the nucleus, and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains regulate protein association and selective oligomerization among zinc-finger proteins.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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