Thermo Fisher Scientific PEG3 Polyclonal Antibody
Thermo Fisher Scientific PEG3 Polyclonal Antibody는 인간 PEG3 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 증식 및 종양 억제 연구에 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PEG3. Recombinant protein control fragment (Product #RP-89445). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645378 |
Product Specific Information
Immunogen sequence:
SSNVREYQKA RAKKKYIEHR SNETSVIHSL PFGEQTFRPR GMLYECQECG ECFAHSSDLT EHQKIHDREK PSGSRNYEWS VIRSLAPTDP QTSYAQEQYA KEQARNKCKD FRQFFATSED LNTNQKIYDQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 68%
- Rat: 69%
Target Information
In humans, ZIM2 and PEG3 are treated as two distinct genes sharing multiple 5′ exons and a common promoter, both paternally expressed. Alternative splicing connects shared 5′ exons either with exons unique to ZIM2 or PEG3.
In other mammals, ZIM2 is not imprinted, and the genes do not share exons. Human PEG3 belongs to the Kruppel C2H2-type zinc finger protein family, involved in cell proliferation and p53-mediated apoptosis. PEG3 also exhibits tumor suppressor activity in glioma and ovarian cells.
Alternative splicing of PEG3 results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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