Thermo Fisher Scientific MEMO1 Polyclonal Antibody
MEMO1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 고순도 항체(>95%)로 세포 이동 및 ERBB2 신호 연구에 적합. 연구용으로만 사용.
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Thermo Fisher Scientific MEMO1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human MEMO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720150 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
MEMO1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton and acts as a mediator of ERBB2 signaling.
The MEMO1-RHOA-DIAPH1 signaling pathway plays a key role in ERBB2-dependent stabilization of microtubules at the cell cortex.
It regulates localization of APC and CLASP2 to the cell membrane via GSK3B activity control. Membrane-bound APC enables MACF1 localization, essential for microtubule capture and stabilization.
MEMO1 is required for breast carcinoma cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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