Thermo Fisher Scientific PML Polyclonal Antibody
PML 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, IP 등에 사용 가능. 0.2 mg/mL 액상 형태로 제공되며, 4°C 보관. 연구용으로 DNA 손상 인식 및 유비퀴틴 경로 관련 연구에 적합.
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Thermo Fisher Scientific PML Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of promyelocytic leukemia (PML) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, involved in nucleotide excision repair (NER).
It interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair.
This protein contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome and ubiquitin protein ligase E6AP, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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