Thermo Fisher Scientific LIMS1 Polyclonal Antibody
LIMS1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human LIMS1 (amino acids 1–325, UniProt ID: P48059-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720652 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The LIMS1 gene encodes an adaptor protein containing five LIM domains (double zinc fingers). This protein is involved in integrin signaling through LIM domain-mediated interaction with integrin-linked kinase found in focal adhesion plaques. It likely acts as a bridge linking integrin-linked kinase to NCK adaptor protein 2, participating in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells suggests a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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