Thermo Fisher Scientific EWSR1 Recombinant Rabbit Monoclonal Antibody (23GB1590)
EWSR1 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, ICC/IF, Flow cytometry에 적합하며, 높은 특이성과 재현성을 제공. HEK293F 발현 시스템 기반으로 정제된 액상 형태, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1590 |
| Immunogen | A synthesized peptide derived from human EWSR1 (100–162AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a multifunctional protein involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and transcription factor genes result in chimeric proteins implicated in tumorigenesis. These chimeric proteins typically consist of the N-terminal activation domain of EWSR1 fused to the C-terminal DNA-binding domain of the transcription factor. Mutations in this gene, particularly translocations, are associated with Ewing sarcoma and other tumors. Alternative splicing generates multiple transcript variants, and related pseudogenes are found on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-53122_EWSR1_Q01844-1_Rabbit.svg, MA5-53122_EWSR1_Q01844-1_Rabbit_PDP.jpeg)
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