Thermo Fisher Scientific ATP6V1C2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji
• Predicted reactivity: Mouse (89%), Rat (90%), Bovine (92%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase-dependent organelle acidification is necessary for intracellular processes such as:

• Protein sorting
• Zymogen activation
• Receptor-mediated endocytosis
• Synaptic vesicle proton gradient generation

V-ATPase consists of a cytosolic V1 domain and a transmembrane V0 domain.
The V1 domain includes three A, three B, and two G subunits, as well as C, D, E, F, and H subunits, and contains the ATP catalytic site.
This gene encodes alternate transcriptional splice variants producing different V1 domain C subunit isoforms.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.