
Thermo Fisher Scientific Norepinephrine Transporter Polyclonal Antibody, Biotin
노르에피네프린 수송체(NET)를 인식하는 Biotin 결합 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인체, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to N-terminal amino acids unique to noradrenaline transporter protein. Antibodies raised using linear, multiple antigenic peptides or cyclic peptide methodology. |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Norepinephrine Transporter (NET, or noradrenaline transporter, NAT) is a monoamine transporter responsible for reuptake of noradrenaline from the synaptic cleft back into presynaptic vesicles for storage. It also transports dopamine to a lesser extent. Decreased NET levels have been observed in the locus coeruleus of patients with major depression. NET is a pharmacological target for cocaine, amphetamines, and various antidepressants such as SNRIs and TCAs. Genetic deficits in NET have been associated with ADHD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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