Thermo Fisher Scientific TGFBR2 Recombinant Rabbit Monoclonal Antibody (8A3Q9)
TGFBR2 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC(P), ELISA에 사용 가능. 인간 및 생쥐 반응성. HEK293 세포에서 발현된 재조합 항체로 높은 특이성과 재현성을 제공. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:9,600 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8A3Q9 |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human TGF beta Receptor II (TGFBR2) (NP_003233.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.203 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093813 |
Product Specific Information
Immunogen sequence:
TWETGKTRKL MEFSEHCAII LEDDRSDISS TCANNINHNT ELLPIELDTL VGKGRFAEVY KAKLKQNTSE QFETVAVKIF PYEEYASWKT EKDIFSDINL K
Target Information
Transforming Growth Factor, beta receptor 2 (TGFBR2; also known as AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It plays a critical role in regulating cell proliferation.
TGFBR2 encodes the gamma subunit of the catalytic core of mitochondrial ATP synthase, which catalyzes ATP synthesis using a proton gradient across the inner mitochondrial membrane during oxidative phosphorylation.
Alternative splicing results in multiple transcript variants encoding different isoforms, and a pseudogene exists on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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