Thermo Fisher Scientific Tyrosinase (Melanoma Marker) Monoclonal Antibody (TYR/3826)
Tyrosinase 단백질을 표적으로 하는 흑색종 마커 단일클론 항체. IHC(P), IHC(PFA), Peptide Array에 사용 가능. Human 반응성, Mouse IgG2b, kappa 아이소타입. 4°C 보관, 동결 금지. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TYR/3826 |
| Immunogen | Recombinant full-length human Tyrosinase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The enzyme encoded by this gene catalyzes the first two steps, and at least one subsequent step, in the conversion of tyrosine to melanin. It exhibits both tyrosine hydroxylase and dopa oxidase activities and requires copper for function. Mutations in this gene cause oculocutaneous albinism, while nonpathologic polymorphisms contribute to variation in skin pigmentation. The human genome also contains a pseudogene similar to the 3′ half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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