Thermo Fisher Scientific Phospho-MARK Pan (Thr215) Polyclonal Antibody
인간 MARK1~4 단백질의 Thr215 인산화 부위에 특이적인 폴리클로날 항체입니다. 면역조직화학(IHC) 실험에 적합하며, 액상 형태로 제공됩니다. 세포 극성 및 미세소관 안정성 연구에 활용 가능합니다. -20°C에서 보관합니다.
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Thermo Fisher Scientific Phospho-MARK Pan (Thr215) Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:50–1:100
Publications: [References available upon request]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human MARK1/2/3/4 around the phosphorylation site of Thr215 (L-D-TP-F-C) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555267 |
Target Information
MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. These kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability.
MARK2 (EMK1) is involved in the control of cell polarity, microtubule stability, and cancer. MARK3 is associated with DNA damage response and pancreatic carcinogenesis. MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1 domain. RT-PCR analysis shows upregulated MARK4 expression in most hepatocellular carcinoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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