Thermo Fisher Scientific DACH2 Polyclonal Antibody
인간 및 생쥐 DACH2 단백질을 검출하는 Thermo Fisher Scientific의 다클론 항체입니다. Western blot과 동결 절편 면역조직화학에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 무보존제 PBS 용액 형태로 제공되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 5–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human DACH2 (Gln419–Gln583) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605976 |
Product Specific Information
This antibody detects endogenous human and mouse DACH2 in Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The DACH2 gene encodes a protein similar to the Drosophila dachshund transcription factor, which is involved in cell fate determination in the eye, limb, and genital disc.
The encoded protein has two characteristic domains:
- N-terminal domain for DNA binding
- C-terminal domain for protein-protein interactions
Located on the X chromosome, DACH2 is subject to inactivation by DNA methylation. It may regulate organogenesis and myogenesis and has been implicated in premature ovarian failure. Multiple transcript variants encoding different isoforms exist.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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