Thermo Fisher Scientific NSDHL Polyclonal Antibody, MaxPab
NSDHL 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 생쥐 반응성. 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 보존제 없이 제공됩니다. 콜레스테롤 생합성 연구용으로 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NSDHL (NP_057006.1, 1 a.a. – approximately 373 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MEPAVSEPMR DQVARTHLTE DTPKVNADIE KVNQNQAKRC TVIGGSGFLG QHMVEQLLAR GYAVNVFDIQ QGFDNPQVRF FLGDLCSRQD LYPALKGVNT VFHCASPPPS SNNKELFYRV NYIGTKNVIE TCKEAGVQKL ILTSSASVIF EGVDIKNGTE DLPYAMKPID YYTETKILQE RAVLGANDPE KNFLTTAIRP HGIFGPRDPQ LVPILIEAAR NGKMKFVIGN GKNLVDFTFV ENVVHGHILA AEQLSRDSTL GGKAFHITND EPIPFWTFLS RILTGLNYEA PKYHIPYWVA YYLALLLSLL VMVISPVIQL QPTFTPMRVA LAGTFHYYSC ERAKKAMGYQ PLVTMDDAME RTVQSFRHLR RVK
Target Information
The NSDHL protein is localized in the endoplasmic reticulum and plays a role in cholesterol biosynthesis.
Mutations in this gene are associated with CHILD syndrome, an X-linked dominant disorder of lipid metabolism that disrupts cholesterol biosynthesis and is typically lethal in males.
Alternatively spliced transcript variants with differing 5′ UTRs have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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