Thermo Fisher Scientific ATGL Recombinant Rabbit Monoclonal Antibody (ARC1192)
Thermo Fisher의 ATGL 재조합 토끼 단클론 항체(ARC1192)는 인간, 마우스, 랫트 시료에 반응하며 Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 제공되며, 지방 분해 효소 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1192 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300–394 of human ATGL / PNPLA2 (NP_065109.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898053 |
Product Specific Information
- Positive Samples: HeLa, A-431, U-87MG, Mouse brain, Mouse kidney, Mouse heart muscle, Rat brain, Rat kidney, Rat heart muscle
- Immunogen Sequence:
LPARLNEALL EACVEPTDLL TTLSNMLPVR LATAMMVPYT LPLESALSFT IRLLEWLPDV PEDIRWMKEQ TGSICQYLVM RAKRKLGRHL PSRLP
Target Information
Lipolytic enzymes are essential for mobilizing fatty acids from triglyceride stores in adipose tissue. Dysfunctional lipolysis can affect energy homeostasis and contribute to obesity and insulin resistance.
Adipose triglyceride lipase (ATGL) catalyzes the initial step in triglyceride hydrolysis and works in coordination with hormone-sensitive lipase (HSL). ATGL is highly expressed in adipose tissue of mice and humans, showing high substrate specificity for triacylglycerol and association with lipid droplets. Inhibition of ATGL significantly reduces total adipose acyl-hydrolase activity, highlighting its key role in lipid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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