Thermo Fisher Scientific MAdCAM1 Monoclonal Antibody (355G8)
MAdCAM1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(P) 분석에 적합합니다. 인간 시료 반응성을 가지며, 단백질 A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 355G8 |
| Immunogen | Recombinant protein MadCAM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: ECV-304 cell lysate
- Cellular location: Membrane
Target Information
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues.
It belongs to the immunoglobulin family and is similar to ICAM1 and VCAM1.
At least seven alternatively spliced transcripts encoding different protein isoforms have been identified, though the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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