Thermo Fisher Scientific Phospho-NDRG1 (Thr346) Recombinant Rabbit Monoclonal Antibody (NDRG1T346-F5)
인간 및 생쥐 반응성을 가진 재조합 토끼 단클론 항체로, NDRG1 Thr346 인산화 부위를 특이적으로 인식합니다. Western blot 및 Flow cytometry에 적합하며, 높은 특이성과 일관된 로트 간 품질을 제공합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Phospho-NDRG1 (Thr346) Recombinant Rabbit Monoclonal Antibody (NDRG1T346-F5)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NDRG1T346-F5 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Thr346 of human phospho NDRG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896916 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
NDRG1 is a 394-amino-acid cytoplasmic protein of the NDRG family. It interacts with APO A-I and A-II and is involved in HDL-mediated cholesterol transport, stress and hormone responses, and cell growth and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction, demyelination, and muscle atrophy.
NDRG1 serves as a differentiation marker and is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and luminal border cells.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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