Thermo Fisher Scientific MASP1 Polyclonal Antibody
MASP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/50% glycerol 용액 형태로 제공. 인간 MASP1 단백질에 반응하며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Mannose Associated Serine Protease 1 (MASP1), amino acid range 20–447 of the target protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903766 |
Target Information
MBL (Mannose-binding lectin) is a key component in the immune response, capable of directly neutralizing invading microorganisms through an antibody-independent mechanism. Mutations in human MBL are associated with immunodeficiency due to reduced complement fixation ability. In humans, MASP-1, MASP-2, MASP-3, and a truncated form of MASP-2 (sMAP or MAp19) form complexes with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3, while the light/B chains differ. Activated MASPs cleave and activate downstream components of the complement pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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