Thermo Fisher Scientific CIRBP Monoclonal Antibody (1C9)
CIRBP 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(1C9)입니다. Western blot, ICC/IF, ELISA에 적합하며 인간 시료에 반응합니다. 고순도의 액상 형태로 제공되며, PBS buffer에 보존되어 연구용으로 사용됩니다.
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Thermo Fisher Scientific CIRBP Monoclonal Antibody (1C9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C9 |
| Immunogen | CIRBP (NP_001271.1, 1–90 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS
Target Information
CIRBP is a cold-inducible mRNA-binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and is essential for cold-induced suppression of cell proliferation. CIRBP binds specifically to the 3’-UTRs of stress-responsive transcripts such as RPA2 and TXN. When overexpressed, it acts as a translational repressor and promotes assembly of stress granules (SGs).
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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