Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI3D4), TrueMAB
Human PTPRE 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D4 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants have been reported:
- One encodes a receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- The other encodes a nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies of the similar gene in mice suggest regulatory roles in RAS-related signal transduction pathways, cytokine-induced SATA signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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