Thermo Fisher Scientific RAD52 Polyclonal Antibody
RAD52 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 핵 내 RAD52 단백질 검출에 유용합니다. 친화 크로마토그래피로 정제된 액상 항체로 연구용으로 사용됩니다.
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- PA5119963
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human RAD52 aa 331–380/418 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913535 |
Product Specific Information
- Positive Control: Hela cell lysate, HL-60 cell lysate, human thyroid tissue, human colon carcinoma tissue, human liver carcinoma tissue, human spleen tissue, mouse liver tissue, rat spleen tissue
- Subcellular Location: Nucleus
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. These breaks are repaired mainly via homologous recombination (HR) or non-homologous end joining (NHEJ). The RAD52 epistasis group, including RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2, plays a key role in homologous recombination. RAD52 catalyzes strand annealing reactions and forms oligomers that attach to single-stranded DNA ends.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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