Thermo Fisher Scientific ERK5 Polyclonal Antibody
ERK5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunoprecipitation에 사용 가능. MAPK7 신호전달 연구에 적합하며, 액상 형태로 제공. 4°C에서 보관하며 1년의 권장 유효기간을 가짐.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 766 and 816 of human extracellular-signal-regulated kinase 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family and is involved in various cellular processes such as proliferation, differentiation, transcription regulation, and development.
MAPK7 is activated by MAP2K5 (MEK5) and participates in downstream signaling of multiple receptors. Upon extracellular stimulation, MAPK7 translocates to the nucleus to regulate gene expression by phosphorylating transcription factors.
Gene deletion of MAPK7 in mice leads to defective blood vessel and cardiac development, resulting in embryonic lethality. It is critical for endothelial function and vascular integrity.
ERK5 is expressed in many adult tissues, including heart, placenta, lung, kidney, and skeletal muscle, but is not detectable in liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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