Thermo Fisher Scientific BTBD7 Polyclonal Antibody
Human BTBD7 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol buffer에 보관됩니다. 세포 형태 변화 및 상피 역학 연구용으로 적합합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–245 of Human BTBD7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549476 |
Product Specific Information
- Recommended positive control: U87-MG
- Predicted reactivity: Mouse (98%), Rat (99%), Zebrafish (81%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BTBD7 acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. It is induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-32003_BTBD7_Q9P203-1_Rabbit.svg / PA5-32003_BTBD7_Q9P203-1_Rabbit_PDP.jpeg)
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