Thermo Fisher Scientific MYBBP1A Polyclonal Antibody
MYBBP1A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, ICC/IF, IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 용액에 0.1% sodium azide 함유. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 2 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the C-terminal region of the human MYBBP1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533449 |
Target Information
The Myb family of transcription factors, including A-, B-, and c-Myb, regulate differentiation, cellular growth, and gene expression.
c-Myb is essential for hematopoietic cell proliferation and differentiation, with levels decreasing as cells mature.
MYBBP1A (Myb-binding protein 1A) is a nuclear protein localized mainly in nucleoli. It interacts with c-Myb and other transcription factors, including the aromatic hydrocarbon receptor (AhR), enhancing AhR-dependent gene expression.
MYBBP1A negatively regulates PPARγ coactivator 1α (PGC-1α) via p38 MAPK and functions as a nucleocytoplasmic shuttling protein using both CRM1-dependent and independent export pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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