Thermo Fisher Scientific ACC1/ACC-alpha Polyclonal Antibody
ACC1/ACC-alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. Human에 반응하며 Mouse, Rat에도 예측 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1925 and 1975 of human acetyl-Coenzyme A carboxylase alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. It is a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by different genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is regulated both long-term (transcriptional and translational levels) and short-term (phosphorylation/dephosphorylation of serine residues and allosteric modulation by citrate or palmitoyl-CoA).
Multiple alternatively spliced transcript variants with distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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