Thermo Fisher Scientific GM-CSF Monoclonal Antibody (A6C6)
인간 GM-CSF를 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 ELISA에 적합. 고순도 Protein G 정제, 2 mg/mL 농도의 액상 형태. PBS/BSA/glycerol buffer에 보존되며 단기 4°C, 장기 -20°C 저장 권장.
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Thermo Fisher Scientific GM-CSF Monoclonal Antibody (A6C6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| ELISA | 1:30,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6C6 |
| Immunogen | Recombinant protein within Human GM-CSF aa 1–144/144 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931404 |
Product Specific Information
- Application notes: Indirect ELISA
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active protein exists as a homodimer in extracellular space.
This gene is located in chromosome region 5q31, associated with 5q- syndrome and acute myelogenous leukemia.
Other genes in this cluster include interleukins 4, 5, and 13.
GM-CSF promotes tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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