Thermo Fisher Scientific Livin Monoclonal Antibody (OTI1B10)
Livin 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. Human 시료 반응성이 있으며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B10 |
| Immunogen | Full length human recombinant protein of BIRC7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724606 |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for their anti-apoptotic activity. A novel human IAP family member, Livin (ML-IAP), contains a single BIR domain and a COOH-terminal RING finger domain. Livin has two splicing variants (298 and 280 amino acids), both containing BIR and RING domains. Both isoforms inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but relatively high in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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