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Thermo Fisher Scientific BTBD12 Polyclonal Antibody
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Thermo Fisher Scientific BTBD12 Polyclonal Antibody

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BTBD12 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. IHC 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.

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pk
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Thermo Fisher Scientific · Thermo Fisher Scientific BTBD12 Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

  • Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 1:100–1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Region between residue 1784 to 1834 of human BTB (POZ) domain containing 12
Conjugate Unconjugated
Form Liquid
Concentration 0.25 mg/mL
Purification Antigen affinity chromatography
Storage buffer TBS, pH 7.0–8.0, with 0.1% BSA
Contains 0.09% sodium azide
Storage conditions 4°C
Shipping conditions Wet ice

Product Specific Information

  • Recommended shelf life: 1 year from date of receipt
  • Based on 100% sequence identity, predicted to react with Gorilla and Chimpanzee

Target Information

This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and forms a multiprotein complex with ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases. It also associates with the MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), protein kinase PLK1, and the uncharacterized protein C20orf94.
The complex is essential for repair of specific DNA lesions and cellular responses to replication fork failure, acting as a docking platform for assembly of multiple structure-specific endonucleases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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