Thermo Fisher Scientific BTBD12 Polyclonal Antibody
BTBD12 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. IHC 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1784 to 1834 of human BTB (POZ) domain containing 12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Gorilla and Chimpanzee
Target Information
This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and forms a multiprotein complex with ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases. It also associates with the MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), protein kinase PLK1, and the uncharacterized protein C20orf94.
The complex is essential for repair of specific DNA lesions and cellular responses to replication fork failure, acting as a docking platform for assembly of multiple structure-specific endonucleases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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