Thermo Fisher Scientific KChIP2 Polyclonal Antibody
Thermo Fisher Scientific의 KChIP2 Polyclonal Antibody는 인간 KCNIP2 단백질을 인식하는 토끼 IgG 폴리클로날 항체입니다. Western blot 및 Immunocytochemistry에 적합하며, 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 2.5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to human KCNIP2 (aa14–aa33, aa65–aa82) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724552 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Cat.
Target Information
Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system.
In the heart, Kv4 channels are involved in the repolarization phase of the action potential.
In the brain, these channels prevent reverse-propagation of action potentials.
Kv4 channels are associated with calcium-binding proteins called KChIPs (Kv channel interacting proteins).
KChIPs bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate their function.
Known KChIPs include:
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; has three isoforms (a, b, c)
- KChIP3: Also known as calsenilin/DREAM; expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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