Thermo Fisher Scientific c-Maf Polyclonal Antibody
Thermo Fisher Scientific의 c-Maf Polyclonal Antibody는 마우스 단백질에 반응하는 토끼 유래 다클론 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog (c-Maf) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
c-Maf is the cellular counterpart of oncogenic v-maf, belonging to the basic region leucine zipper domain transcription factor family. The leucine-zipper domain mediates interaction with LRPICD.
There are two forms of human c-maf mRNA: c-maf-long and c-maf-short. It is identified in the genome of the acute transforming avian retrovirus AS42.
c-maf targets include IL-4 in Th2 cells, crystalline genes in lens fiber cells, insulin gene in islet, p53, and L7, where it acts through binding to a Maf recognition element (MARE).
It regulates Th2 differentiation and lineage-specific hematopoiesis, and functions as a transcription factor for IL-10 gene expression in LPS-activated macrophages.
Chromosomal aberrations involving maf are found in some forms of multiple myeloma. It is expressed in myeloma cell lines and resting monocytes/macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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