Thermo Fisher Scientific MafA Recombinant Rabbit Monoclonal Antibody (BLR067G)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100 - 1:500

-

Immunocytochemistry (ICC/IF)

1:100 - 1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

BLR067G

Immunogen

Peptide representing a region between residue 125 and 175 of human MAF bZIP transcription factor A. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAFA,uniProtId:Q8NHW3-1,ncbiNodeId:9606,antigenRange:125-175,antigenLength:353,antigenImageFileName:A700-067_MAFA_Q8NHW3-1_Rabbit.svg,antigenImageFileNamePDP:A700-067_MAFA_Q8NHW3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1000 µg/mL

Purification

purified

Storage buffer

BBS, pH 7.8 to 8.6

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Target Information

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.