Thermo Fisher Scientific GPS2 Polyclonal Antibody, Biotin
GPS2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체입니다. Western blot, ELISA, IP 등 다양한 응용에 적합하며, 인간·마우스·랫트 반응성을 보입니다. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용에 최적화되어 있습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 250–300 of human G protein pathway suppressor 2 (GPS2) protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein involved in G protein–mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, GPS2 can suppress RAS- and MAPK-mediated signaling and interfere with JNK activity, suggesting a role in signal repression.
The encoded protein is an integral subunit of the NCOR1–HDAC3 complex, which inhibits JNK activation through GPS2 and may provide an alternative mechanism for hormone-mediated antagonism of AP1 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: GPS2-BIOTIN_GPS2_Q13227-1_Rabbit.svg, GPS2-BIOTIN_GPS2_Q13227-1_Rabbit_PDP.jpeg)
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