Thermo Fisher Scientific Bcl11a Recombinant Rabbit Monoclonal Antibody (BLR151J)
Bcl11a 단백질을 표적하는 재조합 토끼 단클론 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 인간 및 생쥐 반응성. 고순도 정제된 액상 형태로 제공되며, 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 6 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR151J |
| Immunogen | Peptide representing a region between residue 785 and the C-terminus (residue 835) of Human B-cell lymphoma/leukemia 11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a C2H2 type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies can deregulate its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A700-151_BCL11A_Q9H165-1_Rabbit.svg, A700-151_BCL11A_Q9H165-1_Rabbit_PDP.jpeg)
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