Thermo Fisher Scientific Mouse IL-13 Recombinant Protein

Applications

• Western Blot (WB): Assay-dependent
• ELISA (ELISA): Assay-dependent
• Control (Ctrl): Assay-dependent

Product Specifications

Product Specific Information

• Carrier-Free
• Stock solutions can be prepared at 50–100 µg/mL in appropriate sterile buffer.
• Carrier protein such as 0.2–1% BSA or HSA can be added when preparing the stock solution.

Target Information

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, inhibiting production of pro-inflammatory cytokines and chemokines, and contributes to allergen-induced asthma through mechanisms independent of IgE and eosinophils.
IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The gene encoding IL-13, together with IL3, IL5, IL4, and CSF2, forms a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.