Thermo Fisher Scientific Aldolase A Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

• Positive Control: 293T, A431, HeLa, HepG2, mouse brain, rat brain
• Predicted Reactivity: Japanese Medaka (83%), Xenopus laevis (86%), Rabbit (98%), Chimpanzee (100%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.
Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development.
Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.