Thermo Fisher Scientific CLDN3 Monoclonal Antibody (OTI1E7), TrueMAB
인간 CLDN3 단백질을 인식하는 Mouse IgG2b 단일클론 항체. Western blot 및 IHC(P) 분석에 최적화. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로 다양한 암 조직의 Claudin 발현 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Full length human recombinant protein of human CLDN3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell-to-cell contact that act as molecular gaskets preventing leakage of ions and water between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin compositions, and differential expression of this gene has been observed in various malignancies including breast, ovarian, liver, urinary, prostate, lung, head and neck, and thyroid cancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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