Thermo Fisher Scientific XRCC3 Monoclonal Antibody (OTI1C1), TrueMAB
XRCC3 단백질을 인식하는 마우스 단클론 항체로, Western Blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. DNA 손상 복구 연구 및 염색체 안정성 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–235 of human XRCC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The XRCC3 gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene complements the Chinese hamster irs1SF mutant, which is hypersensitive to DNA-damaging agents and chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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