Thermo Fisher Scientific REA Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Rabbit Polyclonal 항체. Human, Mouse, Rat 반응성 확인. 항원 친화 크로마토그래피로 정제된 고순도 제품. 단기간 4°C, 장기간 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| in situ PLA (PLA) | - | View 1 publication |
| Immunomicroscopy (IM) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 225–255 amino acids from human PHB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2164780 |
Product Specific Information
This antibody is predicted to react with bovine and rat based on sequence homology.
Target Information
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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