Thermo Fisher Scientific CD66b Monoclonal Antibody (2F12E8)
CD66b 단백질을 인식하는 마우스 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 시료에 반응하며, Protein G로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F12E8 |
| Immunogen | Purified recombinant fragment of human CD66B (AA: 43–178) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091026 |
Target Information
The CD66b (CEACAM8) gene encodes a member of the carcinoembryonic antigen (CEA) family, part of the immunoglobulin superfamily. This family includes cell adhesion molecules and pregnancy-specific glycoproteins located on chromosome 19. CD66b was first identified in bile ducts and later found on leukocytes, epithelial, and endothelial cells. It mediates cell adhesion through homophilic and heterophilic interactions and is involved in processes such as tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation. Multiple transcript variants exist, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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