Thermo Fisher Scientific SEZ6L Polyclonal Antibody
Rabbit polyclonal antibody targeting Human SEZ6L protein. Suitable for research use in neuronal and tumor suppressor studies. Supplied as liquid, unconjugated form at 0.05 mg/mL. Store at 4°C short term or -20°C long term.
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Thermo Fisher Scientific SEZ6L Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEZ6L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790912 |
Product Specific Information
Immunogen sequence:
QFLNLSNSDI LTIYDGDEVM PHILGQYLGN SGPQKLYSST PDLTIQFHSD PAGLIFGKGQ GFIMNYIEVS RNDSCSDLPE IQNGWKTTSH TELVRGARIT YQCDPGYDIV GSDT
Target Information
SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. It is widely expressed and considered a candidate tumor suppressor gene, potentially contributing to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction.
The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several genes on chromosome 22 are associated with Phelan-McDermid syndrome, Neurofibromatosis type 2, autism, and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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