Thermo Fisher Scientific NEK1 Polyclonal Antibody
Human NEK1 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 0.2 mg/mL 농도. DNA 손상 반응 및 세포주기 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEK1. Recombinant protein control fragment (Product #RP-98309). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644601 |
Product Specific Information
- Immunogen sequence:
VLKEQLERKR KEAYEREKKV WEEHLVAKGV KSSDVSPPLG QHETGGSPSK QQMRSVISVT SALKEVGVDS SLTDTRETSE EMQKTNNAIS SKR - Highest antigen sequence identity to the following orthologs:
Mouse – 81%, Rat – 80%
Target Information
NEK1 is a serine/threonine protein kinase related to the NIMA cell cycle regulator and is highly expressed in meiotic germ cells. It may function early in the DNA damage response pathway and participate in polycystic kidney disease and neural cell development. The encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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