Thermo Fisher Scientific SGCE Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
DIQLVHHSAIQ KSTKELRDMS KNREIAWPLS TLPVFHPVTG EIIPPLHTDN YDSTNMPLMQ TQQNLPHQTQ IPQQQTTGKW Y

• Highest antigen sequence identity to orthologs: mouse 94%, rat 96%

Target Information

The SGCE gene encodes the epsilon member of the sarcoglycan family, a group of transmembrane proteins that are part of the dystrophin-glycoprotein complex linking the actin cytoskeleton to the extracellular matrix. Unlike other sarcoglycans mainly expressed in striated muscle, epsilon sarcoglycan is broadly expressed. Mutations in SGCE are associated with myoclonus-dystonia syndrome. The gene is imprinted, showing preferential expression from the paternal allele, and alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.